Enhancing Supplement Efficacy through Timing The timing of supplement intake can be strategically planned based on their properties & effects on the body, to align with the body’s natural rhythms & to achieve the desired outcome. It’s not just about what supplements you take. When you take them & what you take them with can have profound impacts on their efficacy. This includes considering their role in alertness, metabolism, relaxation, solubility (fat vs. water), and post-exercise effects....